Ungraded products supplied by Spectrum are indicative of a grade suitable for general industrial use or research purposes and typically are not suitable for human consumption or therapeutic use. To lessen the chance of inhaling this medicine, apply it in a well-ventilated room (for example, one with free flowing air or with a fan turned on). Pyrethroids are more light-stable and have a longer duration of activity against insects than pyrethrins. umn class: Standard non-polar; Column type: Capillary; Start T: 220 C; CAS no: 51036; Active phase: OV-1; Data type: Kovats RI; Authors: Erdmann, F.; Rochholz, G.; Schutz, H., Retention-indices on OV-1 of approximately 170 commonly used pesticides, Mikrochim. All rights reserved. Piperonyl butoxide is approved as an active substance for use in biocidal products of product-type 18, subject to the specifications and conditions set out in the Annex. How to use Pyrethrins-Piperonyl Butoxide Liquid. It has an Oral LD 50 >7500 mg/kg for rat (Ref.5.3). It is a semisynthetic derivative of safrole. Molecular Structure: Use Type: Synergist. Piperonyl butoxide (PBO) is a synergist used to increase the potency of insecticides like pyrethrins and pyrethroids. Instead, it works with bug killers to increase their effectiveness. PBO is currently used in some insecticide formulations, and has also been suggested as a pretreatment for some pesticide applications. Copyright for NIST Standard Reference Data is governed by CopyCopied, FIPWRIJSWJWJAI-UHFFFAOYSA-N Piperonyl butoxide. This article is for information only. Do NOT use it to treat or manage an actual poison exposure. GENERIC NAME(S): Pyrethrins-Piperonyl Butoxide. Acta, 106, 1992, 219-226. ass: Standard non-polar; Column type: Capillary; CAS no: 51036; Active phase: Ultra-1; Data type: Normal alkane RI; Authors: Tameo, O.; Kiyos, I., Simultaneous determination of pesticides by capillary gas chromatography, Cannot be traslated (in Japan), 14(2), 1991, 109-122. ass: Standard non-polar; Column length: 1.1 m; Column type: Packed; Heat rate: 8.5 K/min; Start T: 50 C; End T: 300 C; CAS no: 51036; Active phase: OV-101; Carrier gas: N2; Substrate: Chromosorb W HP; Data type: Normal alkane RI; Authors: Saxton, W.L., Emergence temperature indices and relative retention times of pesticides and industrial chemicals determined by linear programmed temperature gas chromatography, J. CopyCopied, CSID:5590, http://www.chemspider.com/Chemical-Structure.5590.html (accessed 00:32, Jan 9, 2021) However, NIST makes no warranties to that effect, and NIST Chem Class: Unclassified. m/z Click and drag to zoom, double click to reset zoom Hover over end of line for value. on behalf of the United States of America. Disposal considerations 13.1 Disposal methods Product OTHER NAME(S): Pyrethrins-Piperonyl Butoxide Aerosol, Spray CopyCopied, Validated by Experts, Validated by Users, Non-Validated, Removed by Users, Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, Predicted data is generated using the US Environmental Protection Agency’s EPISuite™, Click to predict properties on the Chemicalize site, For medical information relating to Covid-19, please consult the. CopyCopied, InChI=1S/C19H30O5/c1-3-5-7-20-8-9-21-10-11-22-14-17-13-19-18(23-15-24-19)12-16(17)6-4-2/h12-13H,3-11,14-15H2,1-2H3 Download the identifier in a file. Piperonyl Butoxide, also known as PBO, is an organic compound and a synergist. Review the manufacturer's instruction sheet and carefully follow all directions for your product. This Regulation shall enter into force on the twentieth day following that of its publication in the Official Journal of the European Union. The Koc of piperonyl butoxide ranges from 399-830(1). P0010 Its molecular formula is C 19 H 30 O 5 ; it has a molecular weight of 338.4 g/mol. That is, despite having no pesticidal activity of its own, it enhances the potency of certain pesticides such as carbamates, pyrethrins, pyrethroids, and rotenone. Pyrethrins-Piperonyl Butoxide Aerosol, Spray. The relative density of Piperonyl Butoxide technical material is about 1.058 g/mL at 20°C and its vapour pressure is less than 1.33 x 10-5 Cool containers exposed to heat with water spray and remove them from the fire area if it can be done without risk. © 2018 by the U.S. Secretary of Commerce Multi-ingredient medications containing piperonyl butoxide: permethrin/piperonyl butoxide/pyrethrins topical. Piperonyl butoxide. Piperonyl butoxide (PBO) Piperonyl butoxide is commonly used in spray formulation as a synergist. Compound Structure and Properties. 5- { [2- (2-butoxyethoxy)ethoxy]methyl}-6-propyl-1,3-benzodioxole. PBO is often combined with natural pyrethrins or man-made pyrethroids. Pediculicide; fixed-combination preparation containing pyrethrins (a pediculicide) and piperonyl butoxide (has little or no insecticidal activity but potentiates that of pyrethrins).a Even though it is relatively nontoxic, its extensive use has generated interest among industrial hygienist and regulatory officials. PBO is often combined with natural pyrethrins or man-made pyrethroids. Brand names: Lice Solution, RID Complete Kit, Complete Lice Treatment Kit Drug class(es): topical anti-infectives General description Piperonylbutoxide is a safe insecticide for household and field.Effect of piperonyl butoxide, a synthetic methylenedioxyphenyl inhibitor of cytochrome(s) P450, on the toxicity of organophosphate insecticides to cladoceran test species (Ceriodaphnia dubia, Daphnia magna and Daphnia pulex) has been investigated.Packaging 12.5 Other adverse effects. Chromatogr., 393, 1987, 175-194. class: Semi-standard non-polar; Column diameter: 0.25 mm; Column length: 30 m; Column type: Capillary; Description: 50 0C(1 min) ^ 25 0C/min -> 125 0C ^ 10 0C/min -> 300 0C (10 min); CAS no: 51036; Active phase: 5 % Phenyl methyl siloxane; Carrier gas: Helium; Phase thickness: 0.25 um; Data type: Normal alkane RI; Authors: Department of Food Safety, Ministry of Health; Welfare, Analytical methods for residual compositional substances of agricultural chemicals, feed aadditives, and veterinary drugs in foods, 2006. class: Semi-standard non-polar; Column diameter: 0.25 mm; Column length: 30 m; Column type: Capillary; Description: 50 0C (3 min) ^ 25 0C/min -> 125 0C ^ 10 0C/min -> 275 0C (25 min); CAS no: 51036; Active phase: HP-5; Carrier gas: He; Phase thickness: 0.25 um; Data type: Normal alkane RI; Authors: Lehotay, S.J., Analysis of pesticide residues in mixed fruit and vegetable extracts by direct sample introduction/gas chromatography/tandem mass spectrometry, J. AOAC Int., 83(3), 2000, 680-697. ass: Standard polar; Column type: Capillary; CAS no: 51036; Active phase: Carbowax 20M; Data type: Normal alkane RI; Authors: Tameo, O.; Kiyos, I., Simultaneous determination of pesticides by capillary gas chromatography, Cannot be traslated (in Japan), 14(2), 1991, 109-122. http://www.medchemexpress.com/Nialamide.html, ACD/Labs Percepta Platform - PhysChem Module, US Environmental Protection Agency’s EPISuite™, Compounds with the same molecular formula, Search Google for structures with same skeleton, 155 °C / 0.3 mmHg (460.1052 °C / 760 mmHg), Organic Compound; Pesticide; Ether; Household Toxin; Synthetic Compound. Pesticide properties for Piperonyl butoxide, including approvals, environmental fate, eco-toxicity and human health issues Its boiling point is 203°C at 2.78 mbar. uses its best efforts to deliver a high quality copy of the been selected on the basis of sound scientific judgment. Piperonyl butoxide. According to a classification scheme(2), these Koc values suggest that piperonyl butoxide is expected to have moderate to low mobility in soil. 13. Piperonyl butoxide (PBO), 2- (2-butoxyethoxy)ethyl 6-propyl-piperonyl ether (IUPAC), is an insecticide synergist produced from the condensation of the sodium salt of 2- (2-butoxyethoxy) ethanol and the chloromethyl derivative of hydrogenated safrole (dihydrosafrole) (Figure 99.1 ). Little is known about how insects respond to PBO exposure at the gene transcription level. Formula: C 19 H 30 O 5. This article is for information only. Piperonyl butoxide (PBO) is an insecticide synergist known to inhibit the activity of cytochrome P450 enzymes. piperonyl butoxide,butacide,butocide,ethanol butoxide,pyrenone 606,piperonylbutoxide,6-propylpiperonyl butyl diethylene glycol ether,butyl carbitol 6-propylpiperonyl ether,5-2-2-butoxyethoxy ethoxy methyl-6-propylbenzo d 1,3 dioxole,butoxide synergist: PubChem CID: 5794: ChEBI: CHEBI:32687: IUPAC Name This medicine is harmful if swallowed or inhaled. Piperonyl butoxide with pyrethrins is an ingredient found in medicines to kill lice. structure and mode of action. By being incorporated in polymer substrate by piperonyl butoxide and phthalocyanine, piperonyl butoxide its surface concentration after surface migration is reduced relative to the matrix not containing phthalocyanine.This can be used for the migration controlling piperonyl butoxide, and retains piperonyl butoxide, to obtain lasting effect. errors or omissions in the Database. IUPAC Standard InChI: InChI=1S/C19H30O5/c1-3-5-7-20-8-9-21-10-11-22-14-17-13-19-18 (23-15-24-19)12-16 (17)6-4-2/h12-13H,3-11,14-15H2,1-2H3. Piperonyl butoxide (PBO, Butacide, Ethanol butoxide, Pyrenone 606) is a man-made pesticide synergist, working with insect killers to increase their effectiveness.Piperonyl butoxide is an inhibitor of cytochrome P450 monooxygenases(P450s). Piperonal can be used in the synthesis of some pharmaceutical drugs including tadalafil , [6] L-DOPA , [7] and atrasentan . GC Mass Spectrum. Sources. Formula: C 19 H 30 O 5; Molecular weight: 338.4385; ... CAS Registry Number: 51-03-6; Chemical structure: This structure is also available as a 2d Mol file or as a computed 3d SD file The 3d structure may be viewed using Java or Javascript. Cool containers exposed to flames with water until well after the fire is out. Instead, it works with bug killers to increase their effectiveness. Molecular structure. Molecular Formula C 19 H 30 O 5; Average mass 338.439 Da; Monoisotopic mass 338.209320 Da; ChemSpider ID 5590 NIST Chemistry WebBook. Piperonyl Butoxide (PBO) Acute Toxicity Studies suggest that by interfering with the metabolism of hor-mones, PBO may damage humeral organs such as the thyroid, adrenal, and pituitary glands.13 PBO has a low to moderate toxicity based on short-term laboratory animal studies. Product(s) containing piperonyl butoxide: piperonyl butoxide topical. Evacuate area. The chemical structure is shown in Figure 116.1. Piperonyl butoxide (PBO) is a waxy white solid organic compound used as a synergist component of pesticide formulations. Other . Four metabolites of piperine, viz. According to the U.S. Environmental Protection Agency (EPA), PBO is one of the most commonly used ingredients in Piperonal, like all aldehydes, can be reduced to its alcohol (piperonyl alcohol) or oxidized to give its acid (piperonylic acid). Technology, Office of Data Piperonyl butoxide. Piperonyl Butoxide (PBO) is a pale yellow transparent oily liquid at 20°C with a mildly aromatic odour. By itself, PBO is not designed to harm insects. Based on these results, a pathway for the biotransformation of piperine in rats is proposed. Article 2. The dihydrosafrole moiety containing the methylenedioxyphenyl ring constitutes over half of the PBO molecule by weight … Poisoning occurs when someone swallows the product or too much of the product touches the skin. Piperonyl butoxide and pyrethrins topical (for the skin) is a … Piperonyl butoxide CAS # 51-03-6. InChI=1S/C19H30O5/c1-3-5-7-20-8-9-21-10-11-22-14-17-13-19-18(23-15-24-19)12-16(17)6-4-2/h12-13H,3-11,14-15H2,1-2H3, National Institute of Standards and Molecular weight: 338.4385. Additional Resources About This Chemical Class and Use Type: See the Global Pesticide Resources page for many additional links. piperonylic acid, piperonyl alcohol, piperonal and vanillic acid were identified in the free form in 0-96 hr urine whereas only piperic acid was detected in 0-6 hr bile. Piperonyl Butoxide TG Advice for firefighters Protective actions during firefighting Avoid breathing fire gases or vapours. DO NOT use it to treat or manage an actual poison exposure. Piperonyl butoxide is a semisynthetic derivative of safrole?used as a component of pesticide formulations. no data available. CAS Number: 51-03-6 U.S. EPA PC Code: 067501 CA DPR Chem Code: 486 Molecular Weight: 388.4500. shall not be liable for any damage that may result from Database and to verify that the data contained therein have The acute oral LD50, or dose that kills half the test population, was Poisoning occurs when someone swallows the product or too much of the product touches the skin. 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